Marcia L. Boyle, MS, is the founder of the Immune Deficiency Foundation (IDF), the national non-profit patient organization dedicated to improving the diagnosis, treatment, and quality of life of persons with primary immunodeficiency diseases through advocacy, education, and research (www.primaryimmune.org.) She served as president and CEO until her retirement in August 2017. She grew IDF from 5 volunteers in 1980 to an organization with approximately $10 million a year in revenue in 2017 and a full-time staff of 37. She was a co-founder of the International Patient Organization for Primary Immunodeficiencies (IPOPI), which currently includes the representation of patient organizations from 60 countries around the world. She also served on the Board of Directors of the National Health Council from 2015 to 2017. She was honored as a White House Champion of Change in Precision Medicine in 2015.